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Research Article

Reduced Juvenile Long-Term Depression in Tuberous Sclerosis Complex Is Mitigated in Adults by Compensatory Recruitment of mGluR5 and Erk Signaling

  • Wyatt B. Potter,

    Affiliations: Department of Neuroscience, Medical Science Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Neuroscience Training Program, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    X
  • Trina Basu,

    Affiliations: Department of Neuroscience, Medical Science Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America, Neuroscience Training Program, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    X
  • Kenneth J. O'Riordan,

    Affiliation: Department of Neurology, William S. Middleton Memorial VA Hospital and University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    X
  • Allison Kirchner,

    Affiliation: Department of Neuroscience, Medical Science Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Paul Rutecki,

    Affiliation: Department of Neurology, William S. Middleton Memorial VA Hospital and University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Corinna Burger,

    Affiliation: Department of Neurology, William S. Middleton Memorial VA Hospital and University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    X
  • Avtar Roopra mail

    asroopra@wisc.edu

    Affiliation: Department of Neuroscience, Medical Science Center, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    X
  • Published: August 13, 2013
  • DOI: 10.1371/journal.pbio.1001627

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doi:10.1371/journal.pbio.1001628