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Research Article

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

  • Xin Xiong,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Yan Hao,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Kan Sun,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Jiaxing Li,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Xia Li,

    Affiliation: Neuroscience Center for Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America

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  • Bibhudatta Mishra,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Pushpanjali Soppina,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Chunlai Wu,

    Affiliation: Neuroscience Center for Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America

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  • Richard I. Hume,

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Catherine A. Collins mail

    collinca@umich.edu

    Affiliation: Department of Molecular Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Published: December 04, 2012
  • DOI: 10.1371/journal.pbio.1001440

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