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Research Article

Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons

  • Hennady P. Shulha equal contributor,

    equal contributor Contributed equally to this work with: Hennady P. Shulha, Jessica L. Crisci, Denis Reshetov, Jogender S. Tushir

    Affiliation: Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Jessica L. Crisci equal contributor,

    equal contributor Contributed equally to this work with: Hennady P. Shulha, Jessica L. Crisci, Denis Reshetov, Jogender S. Tushir

    Affiliation: Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Denis Reshetov equal contributor,

    equal contributor Contributed equally to this work with: Hennady P. Shulha, Jessica L. Crisci, Denis Reshetov, Jogender S. Tushir

    Affiliation: Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Moscow, Russian Federation

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  • Jogender S. Tushir equal contributor,

    equal contributor Contributed equally to this work with: Hennady P. Shulha, Jessica L. Crisci, Denis Reshetov, Jogender S. Tushir

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Iris Cheung,

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Rahul Bharadwaj,

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Hsin-Jung Chou,

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Isaac B. Houston,

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Cyril J. Peter,

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Amanda C. Mitchell,

    Affiliation: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Wei-Dong Yao,

    Affiliation: New England Primate Center, Southboro, Massachusetts, United States of America

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  • Richard H. Myers,

    Affiliation: Department of Neurology, Boston University, Boston, Massachusetts, United States of America

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  • Jiang-fan Chen,

    Affiliation: Department of Neurology, Boston University, Boston, Massachusetts, United States of America

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  • Todd M. Preuss,

    Affiliation: Yerkes National Primate Research Center/Emory University, Atlanta, Georgia, United States of America

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  • Evgeny I. Rogaev mail,

    schahram.akbarian@mssm.edu (SA); jeffrey.jensen@epfl.ch (JDJ); evgeny.rogaev@umassmed.edu (EIR); zhiping.weng@umassmed.edu (ZW)

    Affiliations: Department of Human Genetics and Genomics, Vavilov Institute of General Genetics, Moscow, Russian Federation, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Research Center of Mental Health, Russian Academy of Medical Sciences, Moscow, Russian Federation, Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Russian Federation

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  • Jeffrey D. Jensen mail,

    schahram.akbarian@mssm.edu (SA); jeffrey.jensen@epfl.ch (JDJ); evgeny.rogaev@umassmed.edu (EIR); zhiping.weng@umassmed.edu (ZW)

    Affiliations: Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

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  • Zhiping Weng mail,

    schahram.akbarian@mssm.edu (SA); jeffrey.jensen@epfl.ch (JDJ); evgeny.rogaev@umassmed.edu (EIR); zhiping.weng@umassmed.edu (ZW)

    Affiliation: Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Schahram Akbarian mail

    schahram.akbarian@mssm.edu (SA); jeffrey.jensen@epfl.ch (JDJ); evgeny.rogaev@umassmed.edu (EIR); zhiping.weng@umassmed.edu (ZW)

    Affiliations: Brudnick Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Departments of Psychiatry and Neuroscience, Friedman Brain Institute, Mount Sinai School of Medicine, New York, New York, United States of America

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  • Published: November 20, 2012
  • DOI: 10.1371/journal.pbio.1001427

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