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Research Article

Hormonal Signal Amplification Mediates Environmental Conditions during Development and Controls an Irreversible Commitment to Adulthood

  • Oren N. Schaedel,

    Affiliation: Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, Pasadena, California, United States of America

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  • Birgit Gerisch,

    Affiliation: Max-Planck-Institute for Biology of Ageing, Koeln, Germany

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  • Adam Antebi mail,

    pws@caltech.edu (PWS); Antebi@age.mpg.de (AA)

    Affiliations: Max-Planck-Institute for Biology of Ageing, Koeln, Germany, Baylor College of Medicine, Huffington Center on Aging, Houston, Texas, United States of America

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  • Paul W. Sternberg mail

    pws@caltech.edu (PWS); Antebi@age.mpg.de (AA)

    Affiliation: Howard Hughes Medical Institute and Division of Biology, California Institute of Technology, Pasadena, California, United States of America

    X
  • Published: April 10, 2012
  • DOI: 10.1371/journal.pbio.1001306

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