Advertisement
Perspective

Perspective The Perspective section provides experts with a forum to comment on topical or controversial issues of broad interest.

See all article types »

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

  • Carl A. Anderson mail,

    statgen-faculty@sanger.ac.uk

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, United Kingdom

    X
  • Nicole Soranzo,

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, United Kingdom

    X
  • Eleftheria Zeggini,

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, United Kingdom

    X
  • Jeffrey C. Barrett

    Affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1HH, United Kingdom

    X
  • Published: January 18, 2011
  • DOI: 10.1371/journal.pbio.1000580

Media Coverage of this Article

Found additional news media or blog coverage for the article? Please let us know.

Linked Articles

Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results

Naomi R. Wray, Shaun M. Purcell, Peter M. Visscher
Perspective | published 18 Jan 2011 | PLOS Biology
doi:10.1371/journal.pbio.1000579

The Importance of Synthetic Associations Will Only Be Resolved Empirically

David B. Goldstein
Perspective | published 18 Jan 2011 | PLOS Biology
doi:10.1371/journal.pbio.1001008

Common Disease: Are Causative Alleles Common or Rare?

Robert Shields
Editorial | published 18 Jan 2011 | PLOS Biology
doi:10.1371/journal.pbio.1001009