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Research Article

Robust Target Gene Discovery through Transcriptome Perturbations and Genome-Wide Enhancer Predictions in Drosophila Uncovers a Regulatory Basis for Sensory Specification

  • Stein Aerts mail,

    stein.aerts@med.kuleuven.be (SA); bassem.hassan@cme.vib-kuleuven.be (BAH)

    Affiliations: Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium, Laboratory of Computational Biology, Katholieke Universiteit (K.U.) Leuven, Leuven, Belgium, Center for Human Genetics, K.U. Leuven, Leuven, Belgium, Doctoral Program in Molecular and Developmental Genetics, K.U. Leuven Group Biomedicine, Leuven, Belgium

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  • Xiao-Jiang Quan,

    Affiliations: Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium, Center for Human Genetics, K.U. Leuven, Leuven, Belgium

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  • Annelies Claeys,

    Affiliations: Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium, Center for Human Genetics, K.U. Leuven, Leuven, Belgium

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  • Marina Naval Sanchez,

    Affiliations: Laboratory of Computational Biology, Katholieke Universiteit (K.U.) Leuven, Leuven, Belgium, Doctoral Program in Molecular and Developmental Genetics, K.U. Leuven Group Biomedicine, Leuven, Belgium

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  • Phillip Tate,

    Affiliations: Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium, Center for Human Genetics, K.U. Leuven, Leuven, Belgium

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  • Jiekun Yan,

    Affiliations: Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium, Center for Human Genetics, K.U. Leuven, Leuven, Belgium

    X
  • Bassem A. Hassan mail

    stein.aerts@med.kuleuven.be (SA); bassem.hassan@cme.vib-kuleuven.be (BAH)

    Affiliations: Laboratory of Neurogenetics, Department of Molecular and Developmental Genetics, VIB, Leuven, Belgium, Center for Human Genetics, K.U. Leuven, Leuven, Belgium, Doctoral Program in Molecular and Developmental Genetics, K.U. Leuven Group Biomedicine, Leuven, Belgium

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  • Published: July 27, 2010
  • DOI: 10.1371/journal.pbio.1000435

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