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Research Article

mRNA Secondary Structures Fold Sequentially But Exchange Rapidly In Vivo

  • Elisabeth M. Mahen,

    Affiliations: Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

    Current address: Lillehei Heart Institute and Pediatric Hematology, University of Minnesota, Minneapolis, Minnesota, United States of America

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  • Peter Y. Watson,

    Affiliations: Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Joseph W. Cottrell,

    Affiliations: Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Martha J. Fedor mail

    mfedor@scripps.edu

    Affiliations: Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

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  • Published: February 09, 2010
  • DOI: 10.1371/journal.pbio.1000307

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