Advertisement
Research Article

Testing Electrostatic Complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole

  • Daniel A Kraut,

    Affiliation: Department of Biochemistry, Stanford University, Stanford, California, United States of America

    X
  • Paul A Sigala,

    Affiliation: Department of Biochemistry, Stanford University, Stanford, California, United States of America

    X
  • Brandon Pybus,

    Affiliation: Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America

    X
  • Corey W Liu,

    Affiliation: Stanford Magnetic Resonance Laboratory, Stanford University, Stanford, California, United States of America

    X
  • Dagmar Ringe,

    Affiliation: Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America

    X
  • Gregory A Petsko,

    Affiliation: Department of Biochemistry, Brandeis University, Waltham, Massachusetts, United States of America

    X
  • Daniel Herschlag mail

    To whom correspondence should be addressed. E-mail: herschla@stanford.edu

    Affiliation: Department of Biochemistry, Stanford University, Stanford, California, United States of America

    X
  • Published: March 28, 2006
  • DOI: 10.1371/journal.pbio.0040099

Media Coverage of this Article

Found additional news media or blog coverage for the article? Please let us know.

Linked Articles

What Governs Enzyme Activity? For One Enzyme, Charge Contributes Only Weakly

Richard Robinson
Synopsis | published 28 Mar 2006 | PLOS Biology
doi:10.1371/journal.pbio.0040133