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Research Article

Mechanism of Prion Propagation: Amyloid Growth Occurs by Monomer Addition

  • Sean R Collins,

    Affiliation: Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

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  • Adam Douglass,

    Affiliation: Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

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  • Ronald D Vale,

    Affiliation: Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

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  • Jonathan S Weissman mail

    To whom correspondence should be addressed. E-mail: jsw1@itsa.ucsf.edu

    Affiliation: Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, United States of America

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  • Published: September 21, 2004
  • DOI: 10.1371/journal.pbio.0020321

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Linked Articles

A Mechanism of Prion Propagation

Synopsis | published 21 Sep 2004 | PLOS Biology
doi:10.1371/journal.pbio.0020360