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Research Article

A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole

  • Benjamin D. Harrison,

    Affiliation: Department of Genetics, Cell, and Developmental Biology, University of Minnesota–Twin Cities, Minneapolis, Minnesota, United States of America

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  • Jordan Hashemi,

    Affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, United States of America

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  • Maayan Bibi,

    Affiliation: Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel

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  • Rebecca Pulver,

    Affiliation: Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel

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  • Danny Bavli,

    Affiliation: Alexander Grass Center for Bioengineering, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Yaakov Nahmias,

    Affiliation: Alexander Grass Center for Bioengineering, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Melanie Wellington,

    Affiliation: Department of Pediatrics, University of Rochester Medical Center, Rochester, New York, United States of America

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  • Guillermo Sapiro,

    Affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina, United States of America

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  • Judith Berman mail

    jberman@post.tau.ac.il

    Affiliations: Department of Genetics, Cell, and Developmental Biology, University of Minnesota–Twin Cities, Minneapolis, Minnesota, United States of America, Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel

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  • Published: March 18, 2014
  • DOI: 10.1371/journal.pbio.1001815

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Linked Articles

Antifungal Fluconazole Induces Aneuploidy, Sowing the Seeds of Its Own Failure

Richard Robinson
Synopsis | published 18 Mar 2014 | PLOS Biology
doi:10.1371/journal.pbio.1001816