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Research Article

Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism

  • Ross A. Breckenridge mail,

    rbrecke@nimr.mrc.ac.uk

    Affiliations: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom, Division of Medicine, University College London, London, United Kingdom

    X
  • Izabela Piotrowska,

    Affiliation: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

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  • Keat-Eng Ng,

    Affiliation: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

    X
  • Timothy J. Ragan,

    Affiliation: Division of Molecular Structure, MRC–National Institute for Medical Research, London, United Kingdom

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  • James A. West,

    Affiliation: Department of Biochemistry, Cambridge University, Cambridge, United Kingdom

    X
  • Surendra Kotecha,

    Affiliation: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

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  • Norma Towers,

    Affiliation: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

    X
  • Michael Bennett,

    Affiliation: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

    X
  • Petra C. Kienesberger,

    Affiliation: Cardiovascular Research Centre, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

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  • Ryszard T. Smolenski,

    Affiliation: Department of Biochemistry, Medical University of Gdansk, Poland

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  • Hillary K. Siddall,

    Affiliation: Hatter Institute, Institute of Cardiovascular Sciences, University College London, London, United Kingdom

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  • John L. Offer,

    Affiliation: Physical Biochemistry, MRC–National Institute for Medical Research, London, United Kingdom

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  • Mihaela M. Mocanu,

    Affiliation: Hatter Institute, Institute of Cardiovascular Sciences, University College London, London, United Kingdom

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  • Derek M. Yelon,

    Affiliation: Hatter Institute, Institute of Cardiovascular Sciences, University College London, London, United Kingdom

    X
  • Jason R. B. Dyck,

    Affiliation: Cardiovascular Research Centre, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

    X
  • Jules L. Griffin,

    Affiliation: Department of Biochemistry, Cambridge University, Cambridge, United Kingdom

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  • Andrey Y. Abramov,

    Affiliation: Institute of Neurology, University College London, London, United Kingdom

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  • Alex P. Gould,

    Affiliation: Division of Physiology and Metabolism, MRC–National Institute for Medical Research, London, United Kingdom

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  • Timothy J. Mohun

    Affiliation: Developmental Biology, MRC–National Institute for Medical Research, London, United Kingdom

    X
  • Published: September 24, 2013
  • DOI: 10.1371/journal.pbio.1001666

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Linked Articles

Correction: Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism

Ross A. Breckenridge, Izabela Piotrowska, Keat-Eng Ng, Timothy J. Ragan, James A. West, Surendra Kotecha, Norma Towers, Michael Bennett, Petra C. Kienesberger, Ryszard T. Smolenski, Hillary K. Siddall, ...
Correction | published 19 Dec 2013 | PLOS Biology
doi:10.1371/annotation/a9a7f37a-3fa7-4f7f-8310-1339bf5a666e

HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium

Tobias Eckle, Kelley Brodsky, Megan Bonney, Thomas Packard, Jun Han, Christoph H. Borchers, Thomas J. Mariani, Douglas J. Kominsky, Michel Mittelbronn, Holger K. Eltzschig
Research Article | published 24 Sep 2013 | PLOS Biology
doi:10.1371/journal.pbio.1001665

Fine-tuning Metabolic Switches

Caitlin Sedwick
Synopsis | published 24 Sep 2013 | PLOS Biology
doi:10.1371/journal.pbio.1001664