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Research Article

Modulation of Global Low-Frequency Motions Underlies Allosteric Regulation: Demonstration in CRP/FNR Family Transcription Factors

  • Thomas L. Rodgers equal contributor,

    equal contributor Contributed equally to this work with: Thomas L. Rodgers, Philip D. Townsend

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, Department of Chemistry, Durham University, Durham, United Kingdom

    X
  • Philip D. Townsend equal contributor,

    equal contributor Contributed equally to this work with: Thomas L. Rodgers, Philip D. Townsend

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom

    X
  • David Burnell,

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, Department of Chemistry, Durham University, Durham, United Kingdom

    X
  • Matthew L. Jones,

    Affiliation: Department of Physics, Durham University, Durham, United Kingdom

    X
  • Shane A. Richards,

    Affiliation: School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom

    X
  • Tom C. B. McLeish,

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, Department of Chemistry, Durham University, Durham, United Kingdom, Department of Physics, Durham University, Durham, United Kingdom

    X
  • Ehmke Pohl,

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, Department of Chemistry, Durham University, Durham, United Kingdom, School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom

    X
  • Mark R. Wilson,

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, Department of Chemistry, Durham University, Durham, United Kingdom

    X
  • Martin J. Cann mail

    m.j.cann@durham.ac.uk

    Affiliations: Biophysical Sciences Institute, Durham University, Durham, United Kingdom, School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom

    X
  • Published: September 10, 2013
  • DOI: 10.1371/journal.pbio.1001651

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