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Research Article

White-Opaque Switching in Natural MTLa/α Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis, and Sex

  • Jing Xie equal contributor,

    equal contributor Contributed equally to this work with: Jing Xie, Li Tao

    Affiliations: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

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  • Li Tao equal contributor,

    equal contributor Contributed equally to this work with: Jing Xie, Li Tao

    Affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

    X
  • Clarissa J. Nobile,

    Affiliation: Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, United States of America

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  • Yaojun Tong,

    Affiliations: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China, University of Chinese Academy of Sciences, Beijing, China

    X
  • Guobo Guan,

    Affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

    X
  • Yuan Sun,

    Affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

    X
  • Chengjun Cao,

    Affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

    X
  • Aaron D. Hernday,

    Affiliation: Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, United States of America

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  • Alexander D. Johnson,

    Affiliation: Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, United States of America

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  • Lixin Zhang,

    Affiliation: Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

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  • Feng-Yan Bai,

    Affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

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  • Guanghua Huang mail

    huanggh@im.ac.cn

    Affiliation: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

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  • Published: March 26, 2013
  • DOI: 10.1371/journal.pbio.1001525

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