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Research Article

Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans-Infection Through Recognition of Viral Membrane Gangliosides

  • Nuria Izquierdo-Useros mail,

    nizquierdo@irsicaixa.es (NI-U); hans-georg.kraeusslich@med.uni-heidelberg.de (H-GK); jmpicado@irsicaixa.es (JM-P)

    Affiliation: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    X
  • Maier Lorizate equal contributor,

    equal contributor Contributed equally to this work with: Maier Lorizate, Maria C. Puertas, Maria T. Rodriguez-Plata, Nadine Zangger

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

    Current address: Unidad de Biofisica (CSIC-UPV/EHU) and Departamento de Bioquímica, Universidad del Pais Vasco, Bilbao, Spain

    X
  • Maria C. Puertas equal contributor,

    equal contributor Contributed equally to this work with: Maier Lorizate, Maria C. Puertas, Maria T. Rodriguez-Plata, Nadine Zangger

    Affiliation: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    X
  • Maria T. Rodriguez-Plata equal contributor,

    equal contributor Contributed equally to this work with: Maier Lorizate, Maria C. Puertas, Maria T. Rodriguez-Plata, Nadine Zangger

    Affiliation: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    X
  • Nadine Zangger equal contributor,

    equal contributor Contributed equally to this work with: Maier Lorizate, Maria C. Puertas, Maria T. Rodriguez-Plata, Nadine Zangger

    Affiliation: Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland

    X
  • Elina Erikson,

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

    X
  • Maria Pino,

    Affiliation: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    X
  • Itziar Erkizia,

    Affiliation: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    X
  • Bärbel Glass,

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

    X
  • Bonaventura Clotet,

    Affiliation: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain

    X
  • Oliver T. Keppler,

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

    X
  • Amalio Telenti,

    Affiliation: Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland

    X
  • Hans-Georg Kräusslich mail,

    nizquierdo@irsicaixa.es (NI-U); hans-georg.kraeusslich@med.uni-heidelberg.de (H-GK); jmpicado@irsicaixa.es (JM-P)

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

    H-GK and JM-P are joint senior authors on this work.

    X
  • Javier Martinez-Picado mail

    nizquierdo@irsicaixa.es (NI-U); hans-georg.kraeusslich@med.uni-heidelberg.de (H-GK); jmpicado@irsicaixa.es (JM-P)

    Affiliations: AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain, Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

    H-GK and JM-P are joint senior authors on this work.

    X
  • Published: December 18, 2012
  • DOI: 10.1371/journal.pbio.1001448

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