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Research Article

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

  • Gregory D. Rak,

    Affiliations: University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Children's Hospital of Philadelphia Research Institute, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Emily M. Mace,

    Affiliation: Children's Hospital of Philadelphia Research Institute, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Pinaki P. Banerjee,

    Affiliation: Children's Hospital of Philadelphia Research Institute, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Tatyana Svitkina,

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Jordan S. Orange mail

    orange@upenn.edu

    Affiliations: University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Children's Hospital of Philadelphia Research Institute, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

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  • Published: September 13, 2011
  • DOI: 10.1371/journal.pbio.1001151

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Linked Articles

Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

Alice C. N. Brown, Stephane Oddos, Ian M. Dobbie, Juha-Matti Alakoskela, Richard M. Parton, Philipp Eissmann, Mark A. A. Neil, Christopher Dunsby, Paul M. W. French, Ilan Davis, Daniel M. Davis
Research Article | published 13 Sep 2011 | PLOS Biology
doi:10.1371/journal.pbio.1001152