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Research Article

A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors

  • Marijke Brams equal contributor,

    equal contributor Contributed equally to this work with: Marijke Brams, Anshul Pandya

    Affiliation: Laboratory of Structural Neurobiology, KULeuven, Leuven, Belgium

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  • Anshul Pandya equal contributor,

    equal contributor Contributed equally to this work with: Marijke Brams, Anshul Pandya

    Affiliation: Laboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, United States of America

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  • Dmitry Kuzmin,

    Affiliation: Department of Molecular Basis of Neurosignaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia

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  • RenĂ© van Elk,

    Affiliation: Department of Molecular & Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands

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  • Liz Krijnen,

    Affiliation: Laboratory of Structural Neurobiology, KULeuven, Leuven, Belgium

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  • Jerrel L. Yakel,

    Affiliation: Laboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, United States of America

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  • Victor Tsetlin,

    Affiliation: Department of Molecular Basis of Neurosignaling, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia

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  • August B. Smit,

    Affiliation: Department of Molecular & Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands

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  • Chris Ulens mail

    chris.ulens@med.kuleuven.be

    Affiliation: Laboratory of Structural Neurobiology, KULeuven, Leuven, Belgium

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  • Published: March 29, 2011
  • DOI: 10.1371/journal.pbio.1001034

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