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Research Article

Global Functional Atlas of Escherichia coli Encompassing Previously Uncharacterized Proteins

  • Pingzhao Hu equal contributor,

    equal contributor Contributed equally to this work with: Pingzhao Hu, Sarath Chandra Janga, Mohan Babu, J. Javier Díaz-Mejía, Gareth Butland

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Sarath Chandra Janga equal contributor,

    equal contributor Contributed equally to this work with: Pingzhao Hu, Sarath Chandra Janga, Mohan Babu, J. Javier Díaz-Mejía, Gareth Butland

    Affiliations: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada, Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

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  • Mohan Babu equal contributor,

    equal contributor Contributed equally to this work with: Pingzhao Hu, Sarath Chandra Janga, Mohan Babu, J. Javier Díaz-Mejía, Gareth Butland

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • J. Javier Díaz-Mejía equal contributor,

    equal contributor Contributed equally to this work with: Pingzhao Hu, Sarath Chandra Janga, Mohan Babu, J. Javier Díaz-Mejía, Gareth Butland

    Affiliations: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada, Department of Biology, Wilfrid Laurier University, Waterloo, Ontario, Canada

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  • Gareth Butland equal contributor,

    equal contributor Contributed equally to this work with: Pingzhao Hu, Sarath Chandra Janga, Mohan Babu, J. Javier Díaz-Mejía, Gareth Butland

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

    ¤ Current address: Life Science Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

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  • Wenhong Yang,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Oxana Pogoutse,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Xinghua Guo,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Sadhna Phanse,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Peter Wong,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Shamanta Chandran,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Constantine Christopoulos,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Anaies Nazarians-Armavil,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Negin Karimi Nasseri,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Gabriel Musso,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Mehrab Ali,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Nazila Nazemof,

    Affiliation: Department of Biology and Ottawa Institute of Systems Biology, Carleton University, Ottawa, Canada

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  • Veronika Eroukova,

    Affiliation: Department of Biology and Ottawa Institute of Systems Biology, Carleton University, Ottawa, Canada

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  • Ashkan Golshani,

    Affiliation: Department of Biology and Ottawa Institute of Systems Biology, Carleton University, Ottawa, Canada

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  • Alberto Paccanaro,

    Affiliation: Department of Computer Science, Royal Holloway, University of London, Egham, United Kingdom

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  • Jack F Greenblatt,

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Gabriel Moreno-Hagelsieb mail,

    To whom correspondence should be addressed. E-mail: gmoreno@wlu.ca (GM-H); andrew.emili@utoronto.ca (AE)

    Affiliation: Department of Biology, Wilfrid Laurier University, Waterloo, Ontario, Canada

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  • Andrew Emili mail

    To whom correspondence should be addressed. E-mail: gmoreno@wlu.ca (GM-H); andrew.emili@utoronto.ca (AE)

    Affiliation: Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

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  • Published: April 28, 2009
  • DOI: 10.1371/journal.pbio.1000096

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