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Research Article

Transglutaminase 2 Undergoes a Large Conformational Change upon Activation

  • Daniel M Pinkas,

    Affiliation: Department of Chemical Engineering, Stanford University, Stanford, California, United States of America

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  • Pavel Strop,

    Affiliations: Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America, Department of Molecular and Cellular Physiology, Stanford University, Stanford, California, United States of America, Department of Neurology and Neurological Sciences, Stanford University, Stanford, California, United States of America, Department of Structural Biology, Stanford University, Stanford, California, United States of America, Department of Photon Science, Stanford University, Stanford, California, United States of America

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  • Axel T Brunger,

    Affiliations: Howard Hughes Medical Institute, Stanford University, Stanford, California, United States of America, Department of Molecular and Cellular Physiology, Stanford University, Stanford, California, United States of America, Department of Neurology and Neurological Sciences, Stanford University, Stanford, California, United States of America, Department of Structural Biology, Stanford University, Stanford, California, United States of America, Department of Photon Science, Stanford University, Stanford, California, United States of America

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  • Chaitan Khosla mail

    To whom correspondence should be addressed. E-mail: khosla@stanford.edu.

    Affiliations: Department of Chemical Engineering, Stanford University, Stanford, California, United States of America, Department of Chemistry, Stanford University, Stanford, California, United States of America, Department of Biochemistry, Stanford University, Stanford, California, United States of America

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  • Published: December 18, 2007
  • DOI: 10.1371/journal.pbio.0050327

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