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Research Article

Dosage Compensation in the Mouse Balances Up-Regulation and Silencing of X-Linked Genes

  • Hong Lin,

    Affiliation: Chromatin and Gene Expression Group, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham, United Kingdom

    X
  • Vibhor Gupta,

    Affiliations: Chromatin and Gene Expression Group, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham, United Kingdom, BioInformatics and Systems Biology Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

    X
  • Matthew D VerMilyea,

    Affiliation: Chromatin and Gene Expression Group, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham, United Kingdom

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  • Francesco Falciani,

    Affiliation: BioInformatics and Systems Biology Group, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

    X
  • Jeannie T Lee,

    Affiliations: Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Laura P O'Neill,

    Affiliation: Chromatin and Gene Expression Group, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham, United Kingdom

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  • Bryan M Turner mail

    To whom correspondence should be addressed. E-mail: b.m.turner@bham.ac.uk

    Affiliation: Chromatin and Gene Expression Group, Institute of Biomedical Research, University of Birmingham Medical School, Birmingham, United Kingdom

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  • Published: December 11, 2007
  • DOI: 10.1371/journal.pbio.0050326

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