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Research Article

DNA Damage–Induced Bcl-xL Deamidation Is Mediated by NHE-1 Antiport Regulated Intracellular pH

  • Rui Zhao,

    Affiliation: Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham, Cambridge, United Kingdom

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  • David Oxley,

    Affiliation: Protein Technologies Laboratory, The Babraham Institute, Babraham, Cambridge, United Kingdom

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  • Trevor S Smith,

    Affiliation: Protein Technologies Laboratory, The Babraham Institute, Babraham, Cambridge, United Kingdom

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  • George A Follows,

    Affiliation: Department of Haematology, University of Cambridge, Hills Road, Cambridge, United Kingdom

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  • Anthony R Green,

    Affiliation: Department of Haematology, University of Cambridge, Hills Road, Cambridge, United Kingdom

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  • Denis R Alexander mail

    To whom correspondence should be addressed. E-mail: denis.alexander@bbsrc.ac.uk

    Affiliation: Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham, Cambridge, United Kingdom

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  • Published: December 19, 2006
  • DOI: 10.1371/journal.pbio.0050001

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