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Research Article

Target DNA Structure Plays a Critical Role in RAG Transposition

  • Jennifer E Posey,

    Affiliations: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, and Department of Pathology, New York University School of Medicine, New York, New York, United States of America

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  • Malgorzata J Pytlos,

    Affiliation: Laboratory of DNA Structure and Mutagenesis, Center for Genome Research, Institute of Biosciences and Technology, Texas A&M University System Health Sciences Center, Houston, Texas, United States of America

    ¤ Current address: Department of Biological Sciences, Florida Institute of Technology, Melbourne, Florida, United States of America

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  • Richard R Sinden,

    Affiliation: Laboratory of DNA Structure and Mutagenesis, Center for Genome Research, Institute of Biosciences and Technology, Texas A&M University System Health Sciences Center, Houston, Texas, United States of America

    ¤ Current address: Department of Biological Sciences, Florida Institute of Technology, Melbourne, Florida, United States of America

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  • David B Roth mail

    To whom correspondence should be addressed. E-mail: roth@saturn.med.nyu.edu

    Affiliation: Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, and Department of Pathology, New York University School of Medicine, New York, New York, United States of America

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  • Published: October 24, 2006
  • DOI: 10.1371/journal.pbio.0040350

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Can DNA Distortion Turn RAG into a Potent Transposase?

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Synopsis | published 24 Oct 2006 | PLOS Biology
doi:10.1371/journal.pbio.0040390