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Research Article

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

  • Jonathan A Eisen mail,

    To whom correspondence should be addressed. E-mail: jaeisen@ucdavis.edu

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤a Current address: University of California Davis Genome Center, Section of Evolution and Ecology, School of Biological Sciences and Department of Medical Microbiology and Immunology, School of Medicine, University of California Davis, Davis, California, United States of America

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  • Robert S Coyne,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Martin Wu,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Dongying Wu,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Mathangi Thiagarajan,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Jennifer R Wortman,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Jonathan H Badger,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Qinghu Ren,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Paolo Amedeo,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Kristie M Jones,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Luke J Tallon,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Arthur L Delcher,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤b Current address: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

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  • Steven L Salzberg,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤b Current address: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

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  • Joana C Silva,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • Brian J Haas,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

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  • William H Majoros,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤c Current address: Duke Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America

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  • Maryam Farzad,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤d Current address: Agilent Technologies, Inc., Santa Clara, California, United States of America

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  • Jane M Carlton,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤e Current address: Department of Medical Parasitology, New York University School of Medicine, New York, New York, United States of America

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  • Roger K Smith Jr.,

    Affiliation: The Institute for Genomic Research, Rockville, Maryland, United States of America

    ¤f Current address: Dupont Agriculture and Nutrition, Wilmington, Delaware, United States of America

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  • Jyoti Garg,

    Affiliation: Department of Biology, York University, Toronto, Ontario, Canada

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  • Ronald E Pearlman,

    Affiliations: Department of Biology, York University, Toronto, Ontario, Canada, Centre for Research in Mass Spectrometry, York University, Toronto, Ontario, Canada

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  • Kathleen M Karrer,

    Affiliation: Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, United States of America

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  • Lei Sun,

    Affiliation: Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin, United States of America

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  • Gerard Manning,

    Affiliation: Razavi-Newman Center for Bioinformatics, The Salk Institute for Biological Studies, San Diego, California, United States of America

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  • Nels C Elde,

    Affiliation: Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, United States of America

    ¤g Current address: Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Aaron P Turkewitz,

    Affiliation: Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, Illinois, United States of America

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  • David J Asai,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • David E Wilkes,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Yufeng Wang,

    Affiliation: Department of Biology, University of Texas at San Antonio, San Antonio, Texas, United States of America

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  • Hong Cai,

    Affiliation: Department of Electrical Engineering, University of Texas at San Antonio, San Antonio, Texas, United States of America

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  • Kathleen Collins,

    Affiliation: Department of Molecular and Cellular Biology, University of California Berkeley, Berkeley, California, United States of America

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  • B. Andrew Stewart,

    Affiliation: Department of Molecular and Cellular Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Suzanne R Lee,

    Affiliation: Department of Molecular and Cellular Biology, University of California Berkeley, Berkeley, California, United States of America

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  • Katarzyna Wilamowska,

    Affiliation: Department of Computer Science and Engineering, University of Washington, Seattle, Washington, United States of America

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  • Zasha Weinberg,

    Affiliation: Department of Computer Science and Engineering, University of Washington, Seattle, Washington, United States of America

    ¤h Current address: Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, United States of America

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  • Walter L Ruzzo,

    Affiliation: Department of Computer Science and Engineering, University of Washington, Seattle, Washington, United States of America

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  • Dorota Wloga,

    Affiliation: Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

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  • Jacek Gaertig,

    Affiliation: Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

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  • Joseph Frankel,

    Affiliation: Department of Biological Sciences, University of Iowa, Iowa City, Iowa, United States of America

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  • Che-Chia Tsao,

    Affiliation: Department of Biology, University of Rochester, Rochester, New York, United States of America

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  • Martin A Gorovsky,

    Affiliation: Department of Biology, University of Rochester, Rochester, New York, United States of America

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  • Patrick J Keeling,

    Affiliation: Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada

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  • Ross F Waller,

    Affiliation: Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada

    ¤j Current address: School of Botany, The University of Melbourne, Melbourne, Australia

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  • Nicola J Patron,

    Affiliation: Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada

    ¤j Current address: School of Botany, The University of Melbourne, Melbourne, Australia

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  • J. Michael Cherry,

    Affiliation: Department of Genetics, Stanford University, Stanford, California, United States of America

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  • Nicholas A Stover,

    Affiliation: Department of Genetics, Stanford University, Stanford, California, United States of America

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  • Cynthia J Krieger,

    Affiliation: Department of Genetics, Stanford University, Stanford, California, United States of America

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  • Christina del Toro,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

    ¤k Current address: Meharry Medical College, Nashville, Tennessee, United States of America

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  • Hilary F Ryder,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

    ¤l Current address: Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States of America

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  • Sondra C Williamson,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Rebecca A Barbeau,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

    ¤m Current address: Lung Biology Center, University of California San Francisco, San Francisco, California, United States of America

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  • Eileen P Hamilton,

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Eduardo Orias

    Affiliation: Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Published: August 29, 2006
  • DOI: 10.1371/journal.pbio.0040286

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Ciliate Genome Sequence Reveals Unique Features of a Model Eukaryote

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Synopsis | published 29 Aug 2006 | PLOS Biology
doi:10.1371/journal.pbio.0040304