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Research Article

The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response

  • Jan Karlseder,

    Affiliation: Laboratory for Cell Biology and Genetics, Rockefeller University, New York, United States of America

    ¤Current address: Regulatory Biology, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • Kristina Hoke,

    Affiliation: Laboratory for Cell Biology and Genetics, Rockefeller University, New York, United States of America

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  • Olga K Mirzoeva,

    Affiliation: Memorial Sloan–Kettering Cancer Center, New York, New York, United States of America

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  • Christopher Bakkenist,

    Affiliation: Department of Hematology and Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • Michael B Kastan,

    Affiliation: Department of Hematology and Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • John H. J Petrini,

    Affiliation: Memorial Sloan–Kettering Cancer Center, New York, New York, United States of America

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  • Titia de Lange mail

    To whom correspondence should be addressed. E-mail: delange@mail.rockefeller. edu

    Affiliation: Laboratory for Cell Biology and Genetics, Rockefeller University, New York, United States of America

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  • Published: August 17, 2004
  • DOI: 10.1371/journal.pbio.0020240

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Inhibition of the DNA Damage Pathway by a Telomere-Binding Protein

Synopsis | published 17 Aug 2004 | PLOS Biology
doi:10.1371/journal.pbio.0020270