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Research Article

α-Actinin-4-Mediated FSGS: An Inherited Kidney Disease Caused by an Aggregated and Rapidly Degraded Cytoskeletal Protein

  • June Yao,

    Affiliation: Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Tu Cam Le,

    Affiliation: Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Claudine H Kos,

    Affiliation: Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Joel M Henderson,

    Affiliation: Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Phillip G Allen,

    Affiliation: Hematology Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Bradley M Denker,

    Affiliation: Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Martin R Pollak mail

    To whom correspondence should be addressed. E-mail: mpollak@rics.bwh.harvard.edu

    Affiliation: Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: June 15, 2004
  • DOI: 10.1371/journal.pbio.0020167

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Linked Articles

A Protein's Role in Progressive Renal Disease

Synopsis | published 15 Jun 2004 | PLOS Biology
doi:10.1371/journal.pbio.0020194