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Research Article

NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions

  • Kelly N. DuBois,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Sam Alsford,

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • Jennifer M. Holden,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Johanna Buisson,

    Affiliation: Trypanosome Cell Biology Unit, Pasteur Institute and Centre National de la Recherche Scientifique, Paris, France

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  • Michal Swiderski,

    Affiliation: Wellcome Trust Center for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom

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  • Jean-Mathieu Bart,

    Affiliation: Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain

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  • Alexander V. Ratushny,

    Affiliations: The Institute for Systems Biology, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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  • Yakun Wan,

    Affiliation: The Institute for Systems Biology, Seattle, Washington, United States of America

    Current address: The Key Laboratory of Developmental Genes and Human Disease, Ministry of Education, Institute of Life Science, Southeast University, Nanjing, China

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  • Philippe Bastin,

    Affiliation: Trypanosome Cell Biology Unit, Pasteur Institute and Centre National de la Recherche Scientifique, Paris, France

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  • J. David Barry,

    Affiliation: Wellcome Trust Center for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom

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  • Miguel Navarro,

    Affiliation: Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Cientificas, Granada, Spain

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  • David Horn,

    Affiliation: London School of Hygiene & Tropical Medicine, London, United Kingdom

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  • John D. Aitchison,

    Affiliations: The Institute for Systems Biology, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

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  • Michael P. Rout,

    Affiliation: The Rockefeller University, New York, New York, United States of America

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  • Mark C. Field mail

    mcf34@cam.ac.uk

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • Published: March 27, 2012
  • DOI: 10.1371/journal.pbio.1001287

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