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Research Article

Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis

  • Sonia Fieulaine,

    Affiliation: CNRS, ISV, UPR2355, Gif-sur-Yvette, France

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  • Adrien Boularot,

    Affiliation: CNRS, ISV, UPR2355, Gif-sur-Yvette, France

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  • Isabelle Artaud,

    Affiliations: Université Paris Descartes, UMR8601, Paris, France, CNRS, UMR8601, Paris, France

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  • Michel Desmadril,

    Affiliations: Université Paris-Sud, IBBMC, UMR8619, Orsay, France, CNRS, IBBMC, UMR8619, Orsay, France

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  • Frédéric Dardel,

    Affiliations: Université Paris Descartes, UMR8015, Paris, France, CNRS, UMR8015, Paris, France

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  • Thierry Meinnel mail,

    Thierry.Meinnel@isv.cnrs-gif.fr (TM); Carmela.Giglione@isv.cnrs-gif.fr (CG)

    Affiliation: CNRS, ISV, UPR2355, Gif-sur-Yvette, France

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  • Carmela Giglione mail

    Thierry.Meinnel@isv.cnrs-gif.fr (TM); Carmela.Giglione@isv.cnrs-gif.fr (CG)

    Affiliation: CNRS, ISV, UPR2355, Gif-sur-Yvette, France

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  • Published: May 24, 2011
  • DOI: 10.1371/journal.pbio.1001066

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