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Research Article

A Yeast Model of FUS/TLS-Dependent Cytotoxicity

  • Shulin Ju,

    Affiliations: Department of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, United States of America, Department of Neurology and Center for Neurologic Diseases, Harvard Medical School and Brigham & Women's Hospital, Cambridge, Massachusetts, United States of America

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  • Daniel F. Tardiff,

    Affiliations: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Haesun Han,

    Affiliations: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Kanneganti Divya,

    Affiliation: Department of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, United States of America

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  • Quan Zhong,

    Affiliations: Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Lynne E. Maquat,

    Affiliation: Department of Biochemistry and Biophysics and Center for RNA Biology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, United States of America

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  • Daryl A. Bosco,

    Affiliation: Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Lawrence J. Hayward,

    Affiliation: Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Robert H. Brown Jr.,

    Affiliation: Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Susan Lindquist,

    Affiliations: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Dagmar Ringe mail,

    ringe@brandeis.edu (DR); petsko@brandeis.edu (GAP)

    Affiliations: Department of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, United States of America, Department of Neurology and Center for Neurologic Diseases, Harvard Medical School and Brigham & Women's Hospital, Cambridge, Massachusetts, United States of America

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  • Gregory A. Petsko mail

    ringe@brandeis.edu (DR); petsko@brandeis.edu (GAP)

    Affiliations: Department of Biochemistry and Chemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, United States of America, Department of Neurology and Center for Neurologic Diseases, Harvard Medical School and Brigham & Women's Hospital, Cambridge, Massachusetts, United States of America

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  • Published: April 26, 2011
  • DOI: 10.1371/journal.pbio.1001052

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