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Research Article

Dynamics and Design Principles of a Basic Regulatory Architecture Controlling Metabolic Pathways

  • Chen-Shan Chin equal contributor,

    equal contributor Contributed equally to this work with: Chen-Shan Chin, Victor Chubukov

    Affiliation: Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America

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  • Victor Chubukov equal contributor,

    equal contributor Contributed equally to this work with: Chen-Shan Chin, Victor Chubukov

    Affiliations: Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America, Joint Graduate Group in Bioengineering, University of California, Berkeley, and University of California, San Francisco, San Francisco, California, United States of America

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  • Emmitt R Jolly,

    Affiliation: Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America

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  • Joe DeRisi,

    Affiliation: Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America

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  • Hao Li mail

    To whom correspondence should be addressed. E-mail: haoli@genome.ucsf.edu

    Affiliations: Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, United States of America, Joint Graduate Group in Bioengineering, University of California, Berkeley, and University of California, San Francisco, San Francisco, California, United States of America, Center for Theoretical Biology, Peking University, Beijing, China

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  • Published: June 17, 2008
  • DOI: 10.1371/journal.pbio.0060146

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