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Research Article

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

  • Katsuya Tanabe,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Zhonghao Liu,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Satish Patel,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Bradley W Doble,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • Lin Li,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Corentin Cras-Méneur,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Sara C Martinez,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Cris M Welling,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Morris F White,

    Affiliation: Howard Hughes Medical Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Ernesto Bernal-Mizrachi,

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • James R Woodgett,

    Affiliation: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

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  • M. Alan Permutt mail

    To whom correspondence should be addressed. E-mail: apermutt@im.wustl.edu

    Affiliation: Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Published: February 19, 2008
  • DOI: 10.1371/journal.pbio.0060037

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