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Research Article

Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

  • Benjamin Matteson Vincent,

    Affiliations: Microbiology Graduate Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

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  • Alex Kelvin Lancaster,

    Affiliation: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

    Current address: Department of Pathology, Beth Israel Deaconess Medical Center and Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Ruth Scherz-Shouval,

    Affiliation: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

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  • Luke Whitesell,

    Affiliation: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

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  • Susan Lindquist mail

    Lindquist_admin@wi.mit.edu

    Affiliations: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Published: October 29, 2013
  • DOI: 10.1371/journal.pbio.1001692

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