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Research Article

A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms

  • Xiaokun Shu mail,

    rtsien@ucsd.edu (RYT); xiaokun.shu@ucsf.edu (XS)

    Affiliations: Howard Hughes Medical Institute, University of California at San Diego, La Jolla, California, United States of America, Department of Pharmacology, University of California at San Diego, La Jolla, California, United States of America

    Current address: Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California at San Francisco, San Francisco, California, United States of America

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  • Varda Lev-Ram,

    Affiliation: Department of Pharmacology, University of California at San Diego, La Jolla, California, United States of America

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  • Thomas J. Deerinck,

    Affiliation: National Center for Microscopy and Imaging Research, Center for Research on Biological Systems, University of California at San Diego, La Jolla, California, United States of America

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  • Yingchuan Qi,

    Affiliations: Howard Hughes Medical Institute, University of California at San Diego, La Jolla, California, United States of America, Division of Biological Science, Section of Neurobiology, University of California at San Diego, La Jolla, California, United States of America

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  • Ericka B. Ramko,

    Affiliation: National High Magnetic Field Laboratory and Department of Biological Science, The Florida State University, Tallahassee, Florida, United States of America

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  • Michael W. Davidson,

    Affiliation: National High Magnetic Field Laboratory and Department of Biological Science, The Florida State University, Tallahassee, Florida, United States of America

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  • Yishi Jin,

    Affiliations: Howard Hughes Medical Institute, University of California at San Diego, La Jolla, California, United States of America, Division of Biological Science, Section of Neurobiology, University of California at San Diego, La Jolla, California, United States of America

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  • Mark H. Ellisman,

    Affiliations: National Center for Microscopy and Imaging Research, Center for Research on Biological Systems, University of California at San Diego, La Jolla, California, United States of America, Department of Neurosciences, University of California at San Diego, La Jolla, California, United States of America,

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  • Roger Y. Tsien mail

    rtsien@ucsd.edu (RYT); xiaokun.shu@ucsf.edu (XS)

    Affiliations: Howard Hughes Medical Institute, University of California at San Diego, La Jolla, California, United States of America, Department of Pharmacology, University of California at San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, California, United States of America

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  • Published: April 05, 2011
  • DOI: 10.1371/journal.pbio.1001041

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