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Research Article

Binding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species

  • Robert K. Bradley equal contributor,

    equal contributor Contributed equally to this work with: Robert K. Bradley, Xiao-Yong Li

    Affiliations: Department of Mathematics, University of California Berkeley, Berkeley, California, United States of America, Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

    X
  • Xiao-Yong Li equal contributor,

    equal contributor Contributed equally to this work with: Robert K. Bradley, Xiao-Yong Li

    Affiliations: Howard Hughes Medical Institute, University of California Berkeley, Berkeley, California, United States of America, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

    X
  • Cole Trapnell,

    Affiliation: Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

    X
  • Stuart Davidson,

    Affiliation: Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

    X
  • Lior Pachter,

    Affiliations: Department of Mathematics, University of California Berkeley, Berkeley, California, United States of America, Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

    X
  • Hou Cheng Chu,

    Affiliation: Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

    X
  • Leath A. Tonkin,

    Affiliations: California Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, California, United States of America, Vincent J. Coates Genome Sequencing Laboratory, University of California Berkeley, Berkeley, California, United States of America

    X
  • Mark D. Biggin,

    Affiliation: Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

    X
  • Michael B. Eisen mail

    mbeisen@lbl.gov

    Affiliations: Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Howard Hughes Medical Institute, University of California Berkeley, Berkeley, California, United States of America, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America, California Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, California, United States of America

    X
  • Published: March 23, 2010
  • DOI: 10.1371/journal.pbio.1000343

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