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Research Article

Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10

  • Peter W. Janes equal contributor,

    equal contributor Contributed equally to this work with: Peter W. Janes, Sabine H. Wimmer-Kleikamp

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia

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  • Sabine H. Wimmer-Kleikamp equal contributor,

    equal contributor Contributed equally to this work with: Peter W. Janes, Sabine H. Wimmer-Kleikamp

    Affiliations: Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia, European Molecular Biology Laboratory, Heidelberg, Germany, Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany

    Current address: Centre for Vascular Research, School of Medical Sciences, The University of Sydney, Medical Foundation, Camperdown, New South Wales, Australia

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  • Achilleas S. Frangakis,

    Affiliation: European Molecular Biology Laboratory, Heidelberg, Germany

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  • Kane Treble,

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia

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  • Bettina Griesshaber,

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia

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  • Ola Sabet,

    Affiliation: Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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  • Markus Grabenbauer,

    Affiliation: Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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  • Alice Y. Ting,

    Affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Paul Saftig,

    Affiliation: Biochemical Institute, Christian-Albrecht-University, Kiel, Germany

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  • Philippe I. Bastiaens mail,

    philippe.bastiaens@mpi-dortmund.mpg.de (PIB); martin.lackmann@med.monash.edu.au (ML)

    Affiliations: European Molecular Biology Laboratory, Heidelberg, Germany, Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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  • Martin Lackmann mail

    philippe.bastiaens@mpi-dortmund.mpg.de (PIB); martin.lackmann@med.monash.edu.au (ML)

    Affiliation: Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia

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  • Published: October 13, 2009
  • DOI: 10.1371/journal.pbio.1000215

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