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Research Article

Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex Determination

  • Debora Bogani,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Pam Siggers,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Rachel Brixey,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Nick Warr,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Sarah Beddow,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Jessica Edwards,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Debbie Williams,

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Dagmar Wilhelm,

    Affiliation: The Institute of Molecular Bioscience, University of Queensland, Brisbane, Australia

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  • Peter Koopman,

    Affiliation: The Institute of Molecular Bioscience, University of Queensland, Brisbane, Australia

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  • Richard A. Flavell,

    Affiliation: Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Hongbo Chi,

    Affiliation: Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • Harry Ostrer,

    Affiliation: Human Genetics Program, New York University School of Medicine, New York, New York, United States of America

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  • Sara Wells,

    Affiliation: The Mary Lyon Centre, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Michael Cheeseman,

    Affiliations: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom, The Mary Lyon Centre, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Andy Greenfield mail

    a.greenfield@har.mrc.ac.uk

    Affiliation: Mammalian Genetics Unit, Medical Research Council (MRC) Harwell, Oxfordshire, United Kingdom

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  • Published: September 15, 2009
  • DOI: 10.1371/journal.pbio.1000196

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