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Research Article

The Influence of Catalysis on Mad2 Activation Dynamics

  • Marco Simonetta equal contributor,

    equal contributor Contributed equally to this work with: Marco Simonetta, Romilde Manzoni

    Affiliation: Department of Experimental Oncology, European Institute of Oncology, Milan, Italy

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  • Romilde Manzoni equal contributor,

    equal contributor Contributed equally to this work with: Marco Simonetta, Romilde Manzoni

    Affiliation: IFOM, Istituto FIRC di Oncologia Molecolare, Milan, Italy

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  • Roberto Mosca,

    Affiliation: IFOM, Istituto FIRC di Oncologia Molecolare, Milan, Italy

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  • Marina Mapelli,

    Affiliation: Department of Experimental Oncology, European Institute of Oncology, Milan, Italy

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  • Lucia Massimiliano,

    Affiliation: Department of Experimental Oncology, European Institute of Oncology, Milan, Italy

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  • Martin Vink,

    Affiliation: Department of Experimental Oncology, European Institute of Oncology, Milan, Italy

    ¤ Current address: New York Structural Biology Center, New York, New York, United States of America

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  • Bela Novak,

    Affiliation: Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, United Kingdom

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  • Andrea Musacchio mail,

    To whom correspondence should be addressed. E-mail: andrea.ciliberto@ifom-ieo-campus.it (AC); andrea.musacchio@ifom-ieo-campus.it (AM)

    Affiliations: Department of Experimental Oncology, European Institute of Oncology, Milan, Italy, Research Unit of the Italian Institute of Technology (IIT) Foundation at the IFOM-IEO Campus, Milan, Italy

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  • Andrea Ciliberto mail

    To whom correspondence should be addressed. E-mail: andrea.ciliberto@ifom-ieo-campus.it (AC); andrea.musacchio@ifom-ieo-campus.it (AM)

    Affiliation: IFOM, Istituto FIRC di Oncologia Molecolare, Milan, Italy

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  • Published: January 13, 2009
  • DOI: 10.1371/journal.pbio.1000010

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