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Research Article

Nitroimidazole Action in Entamoeba histolytica: A Central Role for Thioredoxin Reductase

  • David Leitsch,

    Affiliation: Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria

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  • Daniel Kolarich,

    Affiliation: Department of Chemistry, University of Natural Resources and Applied Life Sciences, Vienna, Austria

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  • Iain B. H Wilson,

    Affiliation: Department of Chemistry, University of Natural Resources and Applied Life Sciences, Vienna, Austria

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  • Friedrich Altmann,

    Affiliation: Department of Chemistry, University of Natural Resources and Applied Life Sciences, Vienna, Austria

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  • Michael Duchêne mail

    To whom correspondence should be addressed. E-mail: michael.duchene@meduniwien.ac.at

    Affiliation: Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria

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  • Published: July 31, 2007
  • DOI: 10.1371/journal.pbio.0050211

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