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Research Article

Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

  • Takaharu Okada equal contributor,

    equal contributor Contributed equally to this work with: Takaharu Okada, Mark J Miller

    Affiliation: Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

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  • Mark J Miller equal contributor,

    equal contributor Contributed equally to this work with: Takaharu Okada, Mark J Miller

    Affiliation: Department of Physiology and Biophysics, University of California, Irvine, California, United States of America

    ¤a Current address: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

    X
  • Ian Parker,

    Affiliation: Department of Neurobiology and Behavior, University of California, Irvine, California, United States of America

    X
  • Matthew F Krummel,

    Affiliation: Department of Pathology, University of California, San Francisco, California, United States of America

    X
  • Margaret Neighbors,

    Affiliation: Department of Immunobiology, DNAX Research Institute, Palo Alto, California, United States of America

    ¤b Current address: Maxygen, Redwood City, California, United States of America

    X
  • Suzanne B Hartley,

    Affiliation: Department of Immunobiology, DNAX Research Institute, Palo Alto, California, United States of America

    ¤c Current address: Ainslie, ACT, Australia

    X
  • Anne O'Garra,

    Affiliation: Department of Immunobiology, DNAX Research Institute, Palo Alto, California, United States of America

    ¤d Current address: Laboratory of Immunoregulation, The National Institute for Medical Research, London, United Kingdom

    X
  • Michael D Cahalan mail,

    To whom correspondence should be addressed. E-mail: mcahalan@uci.edu (MC), Email: cyster@itsa.ucsf.edu (JC)

    Affiliation: Department of Physiology and Biophysics, University of California, Irvine, California, United States of America

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  • Jason G Cyster mail

    To whom correspondence should be addressed. E-mail: mcahalan@uci.edu (MC), Email: cyster@itsa.ucsf.edu (JC)

    Affiliation: Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

    X
  • Published: May 03, 2005
  • DOI: 10.1371/journal.pbio.0030150

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