05/23/2025
Research Article
If it takes time for the brain to process information, how are we able to interact with moving objects, such as catching a flying ball? William Turner, Hinze Hogendoorn and co-workers provide evidence of multi-stage motion extrapolation occurring in the human brain, shifting the represented position of moving objects closer to real time.
Image credit: pbio.3003189
Current Issue April 2025
05/22/2025
Research Article
Fungal infections are difficult to treat due to drug resistance, and limited research tools make antifungal discovery challenging. Blake Billmyre, Sarah Zanders and co-authors develop a high-throughput TN-seq system in Cryptococcus neoformans, identifying over 1,000 essential genes and revealing a role for essential mitochondrial genes in fluconazole sensitivity.
Image credit: pbio.3003184
05/21/2025
Research Article
Cells reallocate their limited energy for cellular maintenance in response to nutrient scarcity at the expense of other processes, but how this trade-off is achieved remains unknown. Xi Feng, Shanshan Pang, Haiqing Tang and colleagues show that the nucleolar RNA exosome surveillance mechanism can be temporarily inhibited, reducing translation in C. elegans to facilitate adaptation to starvation.
Image credit: pbio.3003190
05/21/2025
Research Article
Bacteria use molecular weapons or toxins to outcompete rivals, but their horizontal gene transfer (HGT) can undermine this advantage. Elisa Granato, Jacob Palmer, Kevin Foster and co-workers show that HGT of toxin plasmids is rare but the recipient bacteria can thrive under relaxed nutrient competition, reshaping bacterial warfare dynamics.
Image credit: pbio.3003095
05/20/2025
Research Article
The medial prefrontal cortex (mPFC) is a key brain area for pain sensation and chronic pain. Shu-Ting Bao, Jun-Li Cao, Cheng Xiao, Chunyi Zhou and co-authors show that modulation of a circuit projecting from the nucleus reuniens of the thalamus to the mPFC improves neural and behavioral indicators of chronic pain in mice.
Image credit: pbio.3003170
05/20/2025
Update Article
Early in the evolution of life a biochemical network was encapsulated within a membrane compartment. Olivia Goode, Urszula Łapińska, Stefano Pagliara, Thomas Richards and colleagues show that specific membrane forms can select for stereochemical compounds which match the pattern of stereochemistry used by all known living things.
Image credit: pbio.3003155
05/20/2025
Perspective
Increasing concerns over the welfare of captive cetaceans have led to calls for their transfer to sanctuaries. This Perspective describes an unprecedented collaboration to develop the first accreditation guidelines for authentic ocean sanctuaries.
Image credit: pbio.3003166
05/15/2025
Perspective
To what extent can we predict future pathogenic microbes? Arturo Casadevall discusses why complex requirements for virulence and dynamic host-microbe interactions make probabilistic predictions difficult, but not impossible.
Image credit: pbio.3003162
05/07/2025
Consensus View
Vertebrate photoreceptors have been studied for well over a century, but a fixed nomenclature across species has been lacking. This Consensus View proposes a new consolidated and pan-vertebrate naming system for the rod and cone photoreceptors of the eye.
Image credit: pbio.3003157
05/07/2025
Perspective
Interferon is a central component of the vertebrate antiviral response. John Schoggins highlights recent findings that suggest a refined ‘limited set’ model of its activity, in which distinct viruses are targeted by small subsets of the induced gene repertoire.
Image credit: pbio.3003154
Neurotechnology offers unprecedented opportunities to treat neural disorders, restore brain function and enhance cognitive abilities. This collection explores the present and possible futures of neurotechnology to improve human health and cognition.
Translating conservation and biodiversity research from the field into the real world is a complex problem. This collection discusses issues around economics, policy, and how to do research that answers questions that decision makers have.
Symbiosis research has become a holistic and pervasive field with a mature theoretical basis. This collection showcases symbiotic relationships across the tree of life, exploring their evolutionary basis and underlying mechanisms.
PLOS Biology is 20 and we are celebrating with a collection that contains articles that look back at landmark studies that we published, others that look past and future, and others discussing how publishing and open science have evolved and what is to come.
.
This collection explores engineering strategies to help us adapt plants to a changing climate, including breeding techniques, genome engineering, synthetic biology and microbiome engineering.
May 26 - 28
Meet Associate Editor Melissa Vazquez Hernandez (mvazquezhernandez@plos.org)
June 10 - 13
Meet removetly Magazine Senior Editor Joanna Clarke (jclarke@plos.org)
June 16 - 20
Meet Senior Editor Roli Roberts (rroberts@plos.org)
June 22 - 27
Meet Editor in Chief Nonia Pariente (npariente@plos.org)
June 24 - 27
Meet Associate Editor Melissa Vazquez Hernandez (mvazquezhernandez@plos.org)
Connect with Us