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Research Article

Mechanotransduction In Vivo by Repeated Talin Stretch-Relaxation Events Depends upon Vinculin

  • Felix Margadant mail,

    felix@margadant.ch

    Affiliation: Research Centre of Excellence in Mechanobiology, National University of Singapore, Singapore

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  • Li Li Chew,

    Affiliation: Research Centre of Excellence in Mechanobiology, National University of Singapore, Singapore

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  • Xian Hu,

    Affiliation: Research Centre of Excellence in Mechanobiology, National University of Singapore, Singapore

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  • Hanry Yu,

    Affiliation: Research Centre of Excellence in Mechanobiology, National University of Singapore, Singapore

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  • Neil Bate,

    Affiliation: Department of Biochemistry, University of Leicester, Leicester, United Kingdom

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  • Xian Zhang,

    Affiliation: Department of Biological Sciences, Columbia University, New York, New York, United States of America

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  • Michael Sheetz

    Affiliation: Department of Biological Sciences, Columbia University, New York, New York, United States of America

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  • Published: December 20, 2011
  • DOI: 10.1371/journal.pbio.1001223

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