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Research Article

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock

  • Gila Arad equal contributor,

    equal contributor Contributed equally to this work with: Gila Arad, Revital Levy

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Revital Levy equal contributor,

    equal contributor Contributed equally to this work with: Gila Arad, Revital Levy

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Iris Nasie,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Dalia Hillman,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Ziv Rotfogel,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Uri Barash,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Emmanuelle Supper,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Tomer Shpilka,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Adi Minis,

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Raymond Kaempfer mail

    kaempfer@hebrew.edu

    Affiliation: Department of Biochemistry and Molecular Biology, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    X
  • Published: September 13, 2011
  • DOI: 10.1371/journal.pbio.1001149

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