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Research Article

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

  • Jose Silva equal contributor mail,

    equal contributor Contributed equally to this work with: Jose Silva, Ornella Barrandon

    To whom correspondence should be addressed. E-mail: jcs64@cscr.cam.ac.uk (JS); austin.smith@cscr.cam.ac.uk (AS)

    Affiliations: Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Ornella Barrandon equal contributor,

    equal contributor Contributed equally to this work with: Jose Silva, Ornella Barrandon

    Affiliations: Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Jennifer Nichols,

    Affiliations: Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom, Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom

    X
  • Jitsutaro Kawaguchi,

    Affiliations: Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Thorold W Theunissen,

    Affiliations: Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Austin Smith mail

    To whom correspondence should be addressed. E-mail: jcs64@cscr.cam.ac.uk (JS); austin.smith@cscr.cam.ac.uk (AS)

    Affiliations: Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

    X
  • Published: October 21, 2008
  • DOI: 10.1371/journal.pbio.0060253

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