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Research Article

Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD+

  • Wolfram Tempel equal contributor,

    equal contributor Contributed equally to this work with: Wolfram Tempel, Wael M Rabeh

    Affiliation: Structural Genomics Consortium and Department of Pharmacology, University of Toronto, Toronto, Canada

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  • Wael M Rabeh equal contributor,

    equal contributor Contributed equally to this work with: Wolfram Tempel, Wael M Rabeh

    Affiliation: Structural Genomics Consortium and Department of Pharmacology, University of Toronto, Toronto, Canada

    X
  • Katrina L Bogan,

    Affiliation: Departments of Genetics and Biochemistry and Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Peter Belenky,

    Affiliation: Departments of Genetics and Biochemistry and Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Marzena Wojcik,

    Affiliation: Departments of Genetics and Biochemistry and Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

    ¤a Current address: Department of Structural Biology, Chair of General Endocrinology, Medical University, Lodz, Poland

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  • Heather F Seidle,

    Affiliation: Departments of Genetics and Biochemistry and Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

    ¤b Current address: American Type Culture Collection, Manassas, Virginia, United States of America

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  • Lyudmila Nedyalkova,

    Affiliation: Structural Genomics Consortium and Department of Pharmacology, University of Toronto, Toronto, Canada

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  • Tianle Yang,

    Affiliation: Department of Pharmacology, Weill Cornell Medical College, New York, New York, United States of America

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  • Anthony A Sauve,

    Affiliation: Department of Pharmacology, Weill Cornell Medical College, New York, New York, United States of America

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  • Hee-Won Park,

    Affiliation: Structural Genomics Consortium and Department of Pharmacology, University of Toronto, Toronto, Canada

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  • Charles Brenner mail

    To whom correspondence should be addressed. E-mail: charles.brenner@dartmouth.edu

    Affiliation: Departments of Genetics and Biochemistry and Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, New Hampshire, United States of America

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  • Published: October 02, 2007
  • DOI: 10.1371/journal.pbio.0050263

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