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Research Article

Ground State Destabilization by Anionic Nucleophiles Contributes to the Activity of Phosphoryl Transfer Enzymes

  • Logan D. Andrews,

    Affiliation: Department of Chemical and Systems Biology, Stanford University, Stanford, California, United States of America

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  • Tim D. Fenn,

    Affiliation: Department of Bioengineering, Stanford University, Stanford, California, United States of America

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  • Daniel Herschlag mail

    herschla@stanford.edu

    Affiliations: Department of Chemical and Systems Biology, Stanford University, Stanford, California, United States of America, Department of Biochemistry, Stanford University, Stanford, California, United States of America

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  • Published: July 02, 2013
  • DOI: 10.1371/journal.pbio.1001599

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