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Research Article

A Lack of Premature Termination Codon Read-Through Efficacy of PTC124 (Ataluren) in a Diverse Array of Reporter Assays

  • Stuart P. McElroy mail,

    s.mcelroy@dundee.ac.uk

    Affiliation: Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, James Black Centre, Dow Street, University of Dundee, Dundee, United Kingdom

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  • Toshifumi Nomura,

    Affiliation: Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan

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  • Leah S. Torrie,

    Affiliation: Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, James Black Centre, Dow Street, University of Dundee, Dundee, United Kingdom

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  • Emma Warbrick,

    Affiliation: Division of Molecular Medicine, College of Life Sciences, Medical Sciences Institute, Dow Street, University of Dundee, Dundee, United Kingdom

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  • Ulrike Gartner,

    Affiliation: Division of Molecular Medicine, College of Life Sciences, Medical Sciences Institute, Dow Street, University of Dundee, Dundee, United Kingdom

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  • Gavin Wood,

    Affiliation: Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, James Black Centre, Dow Street, University of Dundee, Dundee, United Kingdom

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  • W. H. Irwin McLean

    Affiliation: Division of Molecular Medicine, College of Life Sciences, Medical Sciences Institute, Dow Street, University of Dundee, Dundee, United Kingdom

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  • Published: June 25, 2013
  • DOI: 10.1371/journal.pbio.1001593

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