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Research Article

Order–Disorder Transitions Govern Kinetic Cooperativity and Allostery of Monomeric Human Glucokinase

  • Mioara Larion equal contributor,

    equal contributor Contributed equally to this work with: Mioara Larion, Roberto Kopke Salinas

    Affiliation: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America

    X
  • Roberto Kopke Salinas equal contributor,

    equal contributor Contributed equally to this work with: Mioara Larion, Roberto Kopke Salinas

    Affiliations: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America, Institute of Chemistry, University of São Paulo, São Paulo, Brazil, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, United States of America

    X
  • Lei Bruschweiler-Li,

    Affiliations: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, United States of America

    X
  • Brian G. Miller mail,

    miller@chem.fsu.edu (BGM); bruschweiler@magnet.fsu.edu (RB)

    Affiliation: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America

    X
  • Rafael Brüschweiler mail

    miller@chem.fsu.edu (BGM); bruschweiler@magnet.fsu.edu (RB)

    Affiliations: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, United States of America, National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, United States of America

    X
  • Published: December 18, 2012
  • DOI: 10.1371/journal.pbio.1001452

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