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Research Article

An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice

  • Deepak P. Srivastava equal contributor,

    equal contributor Contributed equally to this work with: Deepak P. Srivastava, Kevin M. Woolfrey

    Affiliations: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Neuroscience & Centre for the Cellular Basis of Behaviour, The James Black Centre, King's College London, Institute of Psychiatry, London, United Kingdom

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  • Kevin M. Woolfrey equal contributor,

    equal contributor Contributed equally to this work with: Deepak P. Srivastava, Kevin M. Woolfrey

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

    X
  • Kelly A. Jones,

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

    X
  • Charles T. Anderson,

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

    X
  • Katharine R. Smith,

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

    X
  • Theron A. Russell,

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

    X
  • Hyerin Lee,

    Affiliation: Weinberg College of Arts and Sciences, Northwestern University, Evanston, Illinois, United States of America

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  • Marina V. Yasvoina,

    Affiliation: Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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  • David L. Wokosin,

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

    X
  • P. Hande Ozdinler,

    Affiliations: Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Cognitive Neurology and Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Lurie Cancer Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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  • Gordon M. G. Shepherd,

    Affiliation: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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  • Peter Penzes mail

    p-penzes@northwestern.edu

    Affiliations: Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Lurie Cancer Research Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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  • Published: June 26, 2012
  • DOI: 10.1371/journal.pbio.1001350

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