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Research Article

A Novel Sperm-Delivered Toxin Causes Late-Stage Embryo Lethality and Transmission Ratio Distortion in C. elegans

  • Hannah S. Seidel mail,

    hsseidel@wisc.edu (HSS); leonid@genomics.princeton.edu (LK)

    Affiliations: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America

    Current address: Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Michael Ailion,

    Affiliation: Department of Biology, University of Utah, Salt Lake City, Utah, United States of America

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  • Jialing Li,

    Affiliation: Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Alexander van Oudenaarden,

    Affiliations: Department of Physics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Matthew V. Rockman,

    Affiliations: Department of Biology, New York University, New York, New York, United States of America, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America

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  • Leonid Kruglyak mail

    hsseidel@wisc.edu (HSS); leonid@genomics.princeton.edu (LK)

    Affiliations: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

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  • Published: July 26, 2011
  • DOI: 10.1371/journal.pbio.1001115

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