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Research Article

Generation of Healthy Mice from Gene-Corrected Disease-Specific Induced Pluripotent Stem Cells

  • Guangming Wu equal contributor,

    equal contributor Contributed equally to this work with: Guangming Wu, Na Liu

    Affiliation: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany

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  • Na Liu equal contributor,

    equal contributor Contributed equally to this work with: Guangming Wu, Na Liu

    Affiliations: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany, Junior Research Group Stem Cell Biology, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany

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  • Ina Rittelmeyer,

    Affiliation: Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, and TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany

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  • Amar Deep Sharma,

    Affiliation: Junior Research Group Stem Cell Biology, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany

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  • Malte Sgodda,

    Affiliation: Junior Research Group Stem Cell Biology, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany

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  • Holm Zaehres,

    Affiliation: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany

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  • Martina Bleidißel,

    Affiliation: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany

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  • Boris Greber,

    Affiliation: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany

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  • Luca Gentile,

    Affiliation: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany

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  • Dong Wook Han,

    Affiliations: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany, Department of Stem Cell Biology, Konkuk University, Seoul, Republic of Korea

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  • Cornelia Rudolph,

    Affiliation: Junior Research Group Genetic & Epigenetic Integrity, Cluster of Excellence REBIRTH, Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany

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  • Doris Steinemann,

    Affiliation: Junior Research Group Genetic & Epigenetic Integrity, Cluster of Excellence REBIRTH, Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany

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  • Axel Schambach,

    Affiliation: Junior Research Group Hematopoietic Cell Therapy, Cluster of Excellence REBIRTH, Department Experimental Hematology, Hannover Medical School, Hannover, Germany

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  • Michael Ott,

    Affiliation: Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, and TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany

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  • Hans R. Schöler,

    Affiliations: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany, Junior Research Group Stem Cell Biology, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany, Medical Faculty, University of Münster, Münster, Germany

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  • Tobias Cantz mail

    cantz.tobias@mh-hannover.de

    Affiliations: Max-Planck-Institute for Molecular Biomedicine, Münster, Germany, Junior Research Group Stem Cell Biology, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany

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  • Published: July 12, 2011
  • DOI: 10.1371/journal.pbio.1001099

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