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Research Article

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

  • Zhihui Sun equal contributor,

    equal contributor Contributed equally to this work with: Zhihui Sun, Zamia Diaz

    Affiliation: Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Zamia Diaz equal contributor,

    equal contributor Contributed equally to this work with: Zhihui Sun, Zamia Diaz

    Affiliation: Department of Biochemistry and Biophysics, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Xiaodong Fang,

    Affiliation: Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Michael P. Hart,

    Affiliation: Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Alessandra Chesi,

    Affiliation: Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • James Shorter mail,

    gitler@mail.med.upenn.edu (ADG); jshorter@mail.med.upenn.edu (JS)

    Affiliation: Department of Biochemistry and Biophysics, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Aaron D. Gitler mail

    gitler@mail.med.upenn.edu (ADG); jshorter@mail.med.upenn.edu (JS)

    Affiliation: Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

    X
  • Published: April 26, 2011
  • DOI: 10.1371/journal.pbio.1000614

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