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Research Article

Poised Transcription Factories Prime Silent uPA Gene Prior to Activation

  • Carmelo Ferrai equal contributor,

    equal contributor Contributed equally to this work with: Carmelo Ferrai, Sheila Q. Xie

    Affiliations: Laboratory of Molecular Dynamics of the Nucleus, Division of Genetics and Cell Biology, S. Raffaele Scientific Institute, Milan, Italy, Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom

    X
  • Sheila Q. Xie equal contributor,

    equal contributor Contributed equally to this work with: Carmelo Ferrai, Sheila Q. Xie

    Affiliation: Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom

    X
  • Paolo Luraghi,

    Affiliation: Laboratory of Molecular Dynamics of the Nucleus, Division of Genetics and Cell Biology, S. Raffaele Scientific Institute, Milan, Italy

    Current address: Institute for Cancer Research and Treatment (IRCC), Torino, Italy

    X
  • Davide Munari,

    Affiliation: Laboratory of Molecular Dynamics of the Nucleus, Division of Genetics and Cell Biology, S. Raffaele Scientific Institute, Milan, Italy

    Current address: FIRC Institute of Molecular Oncology (IFOM), Milan, Italy

    X
  • Francisco Ramirez,

    Affiliation: South Ruislip, Middlesex, United Kingdom

    X
  • Miguel R. Branco,

    Affiliation: Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom

    Current address: The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom

    X
  • Ana Pombo mail,

    ana.pombo@csc.mrc.ac.uk (AP); crippa.massimo@hsr.it (MPC)

    Affiliation: Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom

    X
  • Massimo P. Crippa mail

    ana.pombo@csc.mrc.ac.uk (AP); crippa.massimo@hsr.it (MPC)

    Affiliation: Laboratory of Molecular Dynamics of the Nucleus, Division of Genetics and Cell Biology, S. Raffaele Scientific Institute, Milan, Italy

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  • Published: January 05, 2010
  • DOI: 10.1371/journal.pbio.1000270
  • Featured in PLOS Collections

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